Inositol: The Most Underrated Supplement for PCOS
What if reversing PCOS was absolutely possible—and one of the most effective supplements for doing it is something you’ve probably never even heard of?
That supplement is inositol.
While it’s flown under the radar for years, inositol is poised to become the next big thing for women’s health, especially for those looking for natural ways to reverse PCOS. It offers many of the benefits of blood sugar medications like Metformin but with fewer side effects.
In this post, we’ll break down what inositol is, how it works, and why it’s such a game-changer for PCOS.
PCOS and Insulin Resistance
Up to 80% of PCOS cases are driven by insulin resistance.
When your cells stop responding properly to insulin, your body pumps out more and more of it. High insulin levels trigger the ovaries to produce excess androgens (male hormones like testosterone), leading to:
Irregular periods
Cystic acne
Hair loss
Facial hair
Difficulty ovulating
Improving insulin sensitivity is absolutely critical if you want to reverse PCOS—not just manage the symptoms. This is exactly where inositol shines.
What is Inositol?
Inositol is a naturally occurring compound often categorized with B vitamins. It plays a major role in hormone balance, insulin regulation, and cell communication.
The two types of inositol most important for PCOS are:
Myo-Inositol – Helps cells respond to insulin and supports healthy ovarian function
D-Chiro-Inositol – Aids in glucose metabolism and helps lower androgens
The combination of myo- and d-chiro-inositol in the clinically studied 40:1 ratio has been shown to improve ovulation, regulate periods, lower testosterone, and even reduce acne.
Many doctors are now recommending inositol as a natural alternative to Metformin—without the harsh side effects.
Inositol vs. Metformin
Metformin is commonly prescribed for PCOS because it improves insulin sensitivity. However, it often comes with unpleasant side effects like:
Nausea
Diarrhea
B12 deficiency
Many women find Metformin hard to tolerate and eventually stop taking it.
Inositol works similarly by improving insulin signaling—but without the digestive upset or nutrient depletions. Studies show that inositol is just as effective as Metformin for restoring ovulation in women with PCOS, while being better tolerated.
This doesn't mean you should stop medications without consulting your doctor, but if you’re looking for a gentler, more holistic option, inositol is worth considering.
Other Benefits of Inositol
Inositol’s benefits go beyond just improving insulin and hormone balance. It also helps:
Improve sleep quality by regulating neurotransmitters like serotonin and GABA
Reduce anxiety and depression—common issues for women with PCOS
Improve lipid profiles by lowering triglycerides and reducing cardiovascular risk
Many women notice better sleep, better moods, and more stable energy within just a few weeks of taking inositol consistently.
The Inositol Supplement I Recommend
There are many inositol products out there, but not all of them are formulated correctly for PCOS.
I recommend SoWell Health’s SYNCED Inositol formula. It contains:
Myo-inositol and D-chiro-inositol in the ideal clinical 40:1 ratio
Vitamin D and folate which are often low in women with PCOS
SoWell’s SYNCED is formulated specifically for women with PCOS by Dr. Alexandra Sowa, a physician specializing in metabolic health.
You can save 10% with the code KAIT10 (USA only).
Important Note: Inositol Alone Isn’t Enough
While inositol is powerful, no supplement alone will reverse PCOS.
For the best results, pair it with essential lifestyle habits:
Eat at least 30g of protein per meal to stabilize blood sugar and control cravings
Avoid snacking to give insulin levels a chance to drop
Prioritize 7–9 hours of sleep because poor sleep worsens insulin resistance
Strength train 2–3 times per week to improve glucose uptake
Manage stress through walks, meditation, or deep breathing
Supplements are meant to support your habits—not replace them.
Conclusion
If you're dealing with PCOS and insulin resistance, inositol is one of the first supplements you should consider.
It can help:
Lower insulin levels
Improve ovulation
Reduce androgens
Support better mood, sleep, and metabolism
But remember: the magic happens when you combine supplements with the right lifestyle changes. Inositol can be an incredible tool to help you reverse PCOS naturally and feel like yourself again.
